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生物科学系

王振华

发布时间:2026-05-11 来源: 点击数:

王振华、男、中共党员、教授、博士研究生、理学博士学位。

主要研究方向:自由基生物医学。重点关注膳食高脂化介导衰老及老年性疾病发生的生物学基础,聚焦线粒体氧代谢稳态受损介导糖尿病性心肌病发生机制,挖掘南疆沙生药物资源防治膳食高脂化策略开发。

主要学术和教学成果:

科技奖励:

1. 王振华(5/5),青藏高原特色植物资源防治代谢性疾病的物质基础及作用机制研究,青海省自然科学奖,一等奖,2024.

2. 王振华(2/5). 七叶抑苷及其盐在制 备治疗肺部急性炎症的药物中的应用. 烟台市专利奖, 一等奖. 2019.

3. 王振华(5/10). 新疆维吾尔族体脂分布及脂肪组织形态和功能与T2DM遗传易感的相关性实验研究. 新疆生产建设兵团科技进步奖,二等奖. 2016.

4. 王振华(8/15.系统药理学理论和氧还调控技术在筛选评价抗肿瘤药物上的应用. 新疆 生产建设兵团科技进步奖,一等奖. 2014.

5. 王振华(2/5),氧化胁迫介导的电离辐射损伤及抗氧化剂的防护作用,甘肃省自然科学奖,二等奖, 2013.

6. 王振华(3/9). 重离子束辐射联合p53基因治疗肿瘤应用基础研究. 甘肃省科技进步奖,二等奖,2011.

7. 王振华(2/10. 抗肿瘤新药异甘草素药理实验研究,新疆生产建设兵团科技进步奖,二等奖,2009.

学术论文(*表示通讯作者):

1. Wang Man, Shi Xiaobing, Zhou Yufeng, Feng Jianhui, Diao Yining, Li Gang, Wang Zhenhua*, Ma Chengjun*. Nuciferine Ameliorates Lipotoxicity-Mediated Myocardial Ischemia–Reperfusion Injury by Reducing Reverse Electron Transfer Mediated Oxidative Stress. Nutrients. 2026; 18(3), 425.

2. Lin Zikai, Sun Yan, Li Chengzhao, Zhou Xiaowei, Guo Yuting, Wang Zhenhua* and Li Gang*. (7E)-7,8-Dehydroheliobuphthalmin from Platycladus orientalis L.: Isolation, Characterization, and Hair Growth Promotion. International Journal of Molecular Sciences. 2025; 26: 5189.

3. Li Mei, Yang Shuang, Yi Huixiang, Wang Ziying, Xu Bo, Li Gang, Ma Chengjun, Yuan Chengshan* and Wang Zhenhua*. Preparation and evaluation of licochalcone A - integrated casein-pectin nanodelivery system:Insights into its gastrointestinal digestibility and bioavailability. Food Chemistry. 2025; 2025:144633.  

4. Feng Jianhui, Cao Wenhao, Xu Bo, Wang Zhenhua*. Structure-based method for the discovery of selective inhibitors of PED 5 in erectile dysfunction therapy from the Pacific oyster peptides (Crassostrea gigas):Peptidomic analysis, molecular docking, and activity validation. International Journal of Biological Macromolecules. 2025; 295:139494.  

5. Gong Youshun, Guo Nalin, Dai Keyao, Han Bing, Wang Zhenhua*, Ji Haiyu*. Primary structure analysis of cold water-soluble alcohol extract from green tea and the regulatory effects on intestinal flora metabolism. LWT-FOOD SCIENCE AND TECHNOLOGY. 2025; 216:117313.

6. Zhang Lifen, Li Jiaxin, Zhang Wenchan, Yi Huixiang, Zhao Mengjian, Wang Ziying, Li Gang, Xu Bo, Ma Chengjun, Li Jinwei, Li Mei* and Wang Zhenhua*. Functionalized xanthohumol nanoemulsion:fabrication, characterization and bioavailability enhancement of bioactive compounds. Journal of the Science of Food and Agriculture. 2024; 104(5):9442-9450.

7. Zheng Wei, Han Xiao, Han Bing, Li Gang, Gan Jing, Wang Tian, Xu Bo, He Jie, Du Wenxiao, Cao Xiaolin, Wang Zehnhua*. LAR Downregulation Protects the Astrocytic U251 and Cocultured SH-SY5Y Cells in a Rotenone Induced Parkinson’s Disease Cell Model. International Journal of Molecular Sciences. 2023; 24(13):11111.

8. Han Xiao, Han Bing, Zhao Yue, Li Gang, Wang Tian, He Jie, Du Wenxiao, Cao Xiaolin, Gan Jing, Wang Zhenhua* and Wei Zheng*. Rosmarinic Acid Attenuates Rotenone-Induced Neurotoxicity in SH-SY5Y Parkinson's Disease Cell Model through Abl Inhibition. Nutrients. 2022; 14(7):3508.

9. Li Gang, Chu Ming, Tong Yingying, Liang Yuexin, Wang Shenghui, Ma Chengjun Ma, Wang Zhenhua* and Zhou Wenna*. Protective Effects of Hippophae rhamnoides L. Phenylpropanoids on Doxorubicin-Induced Cardiotoxicity in Zebrafish. Molecules 2022, 27(24), 8858.

10. Shaozhi Hou, Yang Song, Di Sun, Shujun Zhu, and Zhenhua Wang*. Xanthohumol-Induced Rat Glioma C6 Cells Death by Triggering Mitochondrial Stress. International Journal of Molecular Sciences. 2021; 22(9):4506.

11. Jin Youcai, Luan Guangxiang, Li Ji, Wang Honglun, Wang Zhenhua* and Bai Bo*. Effect of mtDNA depletion from C6 glioma cells and characteristics of the generated C6ρ0 cells. Molecular Medicine Reports. 2021; 23:265

12. WANG Zhen Hua, SHI Xiao Bing, LI Gang, HAO Xue Yan, YUAN Zhen Zhen, CAO Xiao Hai, WANG Hong Lun, LI Ji and MA Cheng Jun. Safflower Yellow Compounds Alleviate Okadaic Acid-Induced Impairment of Neurite Outgrowth in Differentiated SH-SY5Y Cells. Biomedical and Environmental Sciences. 2020; 33(10):812-816.  

主持在研课题:

1. 新疆维吾尔自治区天池英才-领军人才支持计划(BT-2025-TCYC-0001),2025.01-2027.12250万元。

2. 兵团农业关键核心技术攻关项目,南疆红枣资源高效精准功能食品开发与示范(NYHXGG, 2025AA504) 2025.10-2027.10280.0 万元。

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